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⚠️ For research and laboratory use only. Not for human or animal use.

BPC-157

⚠️ For research and laboratory use only. Not for human or animal use.

BPC-157

55,00 €

BPC-157 is a pentadecapeptide composed of 15 amino acids, partially derived from the Body Protection Compound (BPC) originally isolated from human gastric juice. Preclinical studies have shown that it accelerates the healing of various types of injuries — including muscle, tendon, and ligament damage — while also supporting organ protection and the prevention of gastric ulcers. It acts within the digestive tract to help maintain intestinal integrity and counter conditions such as leaky gut, IBS, and Crohn’s disease. BPC-157 is also known for its analgesic properties and its ability to promote faster skin regeneration by enhancing blood flow and stimulating collagen, reticulin, and new vessel formation, representing a promising research tool in tissue repair processes.

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Laboratory analysis available (COA)Latest tested batch: PC-BPC-2809U — 10mg

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BPC-157

Pentadecapeptide for research on tissue regeneration, angiogenesis, and cellular protection.

What is BPC-157

BPC-157 (Body Protection Compound-157) is a peptide composed of 15 amino acids, partially derived from a natural sequence found in human gastric juice. It is considered a research compound with pronounced cytoprotective and regenerative properties, widely studied in preclinical animal and cell models.

Its natural biological function is to help maintain the integrity of the gastrointestinal mucosa and support tissue healing processes. Several studies have shown that BPC-157 promotes fibroblast proliferation, new blood vessel formation, and collagen synthesis, contributing to the repair of muscles, tendons, ligaments, and mucosal tissues (Staresinic et al., 2003).

Mechanism of Action: Angiogenesis and Tissue Repair

BPC-157 acts through multiple biological mechanisms that cooperate in wound repair. One of the most studied is the stimulation of angiogenesis—the process of forming new blood vessels from existing ones. This occurs partly through activation of the VEGFR2 receptor and modulation of Akt/eNOS signaling pathways, both essential for endothelial cell survival and vascular growth (Chang et al., 2010; Hsieh et al., 2017).

The peptide also influences connective tissue by stimulating fibroblast migration and extracellular matrix deposition. This leads to faster and more stable healing, with improved mechanical strength in the repaired tissues. The combined effects on angiogenesis, collagen formation, and cellular proliferation make BPC-157 one of the most promising peptides for research on tissue regeneration.

Observed Effects on Tissues and Healing

In preclinical studies, BPC-157 has demonstrated versatile biological activity across multiple systems.

Tendon and Ligament Healing

Tendon and ligament injuries typically heal slowly due to limited blood supply. In animal models, BPC-157 significantly improved the regeneration of these tissues, increasing fibroblast density and the formation of well-organized collagen fibers (Novinscak et al., 2008). Research also revealed an increase in key migration-related proteins such as paxillin and FAK, indicating direct stimulation of the cellular repair process.

Muscle and Skin Healing

In muscle injury models, BPC-157 accelerated regeneration and functional recovery, reduced necrosis, and improved vascularization. Similar effects were reported in skin wounds and burns, where BPC-157 enhanced re-epithelialization and the development of higher-quality granulation tissue (Prkacin et al., 2001).

Neurovascular and Gastroprotective Effects

Beyond its local effects, BPC-157 exhibits systemic potential by modulating microcirculation and protecting organs. In ischemic animal models, it improved cerebral perfusion and reduced neuronal damage, suggesting a role in maintaining vascular integrity and nitric oxide balance (Vukojević et al., 2021). In the gastrointestinal tract, BPC-157 protects the mucosa from damage caused by ethanol, indomethacin, and oxidative stress (Šikirić et al., 1996).

Antioxidant and Protective Properties

Several studies have confirmed that BPC-157 reduces oxidative stress and supports cellular defense mechanisms. In rat models, it decreased nitrite, nitrate, and malondialdehyde (MDA) levels—biomarkers of lipid peroxidation and oxidative damage. More recently, delivery through Lactococcus lactis has been shown to increase intestinal concentrations of the peptide and enhance mucosal protection.

Drug Interaction and Cytoprotective Research

Another area of research interest involves BPC-157’s ability to counteract certain drug-induced side effects. Experimental studies demonstrated that it reduces gastric lesions caused by NSAIDs such as ibuprofen and celecoxib. It also protects the heart and nervous system from QTc prolongation and neuromotor disturbances induced by antipsychotic or dopaminergic drugs. These findings position BPC-157 as an important model for research into cytoprotection and oxidative balance.

Notes and Warnings

The BPC-157 provided by Pepticore Aminos is intended exclusively for scientific and laboratory research use. It is not approved for human or animal consumption and must not be used as a medicine or diagnostic tool. All information presented is for educational and research purposes only and is based on publicly available preclinical studies.

mg

10mg

Peptide Technical Data

Product Name BPC-157
CAS Number 137525-51-0
Purity ≥99%
Sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molecular Formula C62H98N16O22
Molecular Weight 1419.5 g/mol
Applications Tissue repair studies, inflammation research, gastrointestinal health investigations, musculoskeletal healing research
Synthesis Method Solid-phase synthesis
Format Lyophilized powder
Appearance White crystalline powder
Solubility Soluble in water or 1% acetic acid
Stability & Storage Stable for 24 months at −20°C (lyophilized). After reconstitution: store at 4°C ≤2 weeks or −20°C ≤6 months.
Shipping Conditions Shipped at room temperature. Upon receipt, store at −20°C.
Regulatory / Compliance Complies with research use only standards. Not for drug, household, or other uses.

Storage

Storage Instructions

All Pepticore Aminos products are manufactured using a lyophilization (freeze-drying) process, which ensures product stability during shipping for up to 3–4 months.

Once reconstituted (mixed with bacteriostatic water), the peptides should be stored in the refrigerator to maintain stability. After reconstitution, they remain stable for up to 30 days.

What is Lyophilization

Lyophilization is a dehydration process, also known as cryodesiccation, in which peptides are first frozen and then exposed to low pressure. Under these conditions, the water in the vial sublimates directly from solid to gas, leaving behind a stable, white crystalline structure (lyophilized peptide).

The white powder can be stored at room temperature until reconstitution with bacteriostatic water.

Storage After Delivery

Keep peptides cool and protected from light. For use within a few days, weeks, or months, simple refrigeration at a temperature of < 4 °C (39 °F) is sufficient.

Lyophilized peptides are generally stable at room temperature for several weeks or longer; if use is expected within a few weeks or months, this storage condition is acceptable.

Long-Term Storage

For periods of several months or years, storage in a −80 °C (−112 °F) freezer is recommended as the optimal solution to preserve peptide stability.

For more information on proper storage techniques, visit:
Peptide Storage Information

Disclaimer - For Research Use Only

The products offered by Pepticore Aminos are intended exclusively for research and laboratory use and are sold only to qualified professionals, institutions, or authorized entities. These products are not intended for human or veterinary consumption, nor for any application involving living organisms, including – but not limited to – diagnostic, therapeutic, or recreational purposes.

By making a purchase, the customer declares that:

  • they are a qualified professional or entity, possessing the necessary competence, training, and facilities for the safe handling of chemical reagents;
  • they will use the product in full compliance with all applicable local, national, and European Union laws and regulations;
  • they will adopt appropriate safety measures during all stages of handling, storage, and disposal.

Prohibited uses:

  • The product must not be used as an Active Pharmaceutical Ingredient (API) in the manufacturing or preparation of medicines intended for humans or animals;
  • Any direct administration or use on humans or animals is strictly prohibited;
  • Pepticore Aminos does not endorse or permit the use of its products for the production, testing, or development of illegal substances.

Regulatory compliance:

Pepticore Aminos does not claim or imply that its products are approved by the European Medicines Agency (EMA), the Food and Drug Administration (FDA), or any other regulatory authority. All information provided is for informational and scientific purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease.

Liability:

L’acquirente si assume ogni responsabilità per la manipolazione, conservazione e utilizzo del prodotto in condizioni sicure e conformi alla legge.
Pepticore Aminos non potrà essere ritenuta responsabile per danni diretti o indiretti derivanti da un uso improprio, dallo stoccaggio non corretto o da un utilizzo non autorizzato del prodotto.
Pepticore Aminos si riserva il diritto di rifiutare la vendita a qualsiasi individuo o ente sospettato di uso improprio dei propri prodotti.

In case of doubts regarding the safe and lawful use of the product, it is recommended to consult a qualified professional experienced in laboratory research.

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